top of page

A septin-Hof1 scaffold at the yeast bud neck binds and organizes actin cables

Mol Biol Cell. 2020 Aug 15;31(18):1988-2001. doi: 10.1091/mbc.E19-12-0693. Epub 2020 Jun 24.

Garabedian MV, Wirshing A, Vakhrusheva A, Turegun B, Sokolova OS, Goode BL. A 

 

Centering and symmetry breaking in confined contracting actomyosin networks

eLife 2020 Apr 21;9. doi: 10.7554/eLife.55368.

Ierushalmi N, Malik-Garbi M, Manhart A, Abu Shah E, Goode BL, Mogilner A, Keren K

 

Genetically-inspired in vitro reconstitution of S. cerevisiae actin cables from seven purified proteins

Molecular Biology of the Cell 2020. Mar 1;31(5):335-347. doi: 10.1091/mbc.E19-10-0576

Pollard LW, Garabedian MV, Alioto SL, Shekhar S, Goode BL.

 

     2019             

 

Synergy between Cyclase-associated protein and Cofilin accelerates actin filament depolymerization by two orders of magnitude

Nature Communications. 2019 Nov 22;10(1):5319. doi: 10.1038/s41467-019-13268-1.

Shekhar S, Chung J, Kondev J, Gelles J and Goode BL.

Scaling behavior in steady-state contracting actomyosin networks

Nature Physics. 2019 May;15(5):509-516. doi: 10.1038/s41567-018-0413-4. Epub 2019 Feb 4.

Maya Malik-Garbi, Niv Ierushalmi, Silvia Jansen, Enas Abu-Shah, Bruce L. Goode, Alex Mogilner and Kinneret Keren

 

The role of APC-mediated actin assembly in microtubule capture and focal adhesion turnover

Journal of Cell Biology. 2019 Oct 7;218(10):3415-3435. doi: 10.1083/jcb.201904165. Epub 2019 Aug 30.

Marie Angeles Juanes, Daniel Isnardon, Ali Badache, Sophie Brasselet, Manos Mavrakis, and Bruce L. Goode

 

Tropomyosin Isoforms differentially tune actin filament length and disassembly

Mol. Biol. Cell. 2019 Mar 1;30(5):671-679. doi: 10.1091/mbc.E18-12-0815. Epub 2019 Jan 16.

Silvia Jansen, and Bruce L. Goode

     2018        

 

A novel mode of Capping Protein-regulation by Twinfilin

eLife 2018;7:e41313

Adam B. Johnston, Denise M. Hilton, Patrick McConnell, Britney Johnson, Meghan T. Harris, Avital Simone, Gaya K. Amarasinghe, John A. Cooper, and Bruce L. Goode

Integrated control of formin-mediated actin assembly by a stationary inhibitor and a mobile activator

Journal of Cell Biology Oct 1;217(10):3512-3530

Mikael V. Garabedian, Tatiana Stanishneva-Konovalova, Chenyu Lou, Thomas J. Rands, Luther W. Pollard, Olga S. Sokolova and Bruce L. Goode

Abp1 promotes Arp2/3 complex-dependent actin nucleation and stabilizes branch junctions by antagonizing GMF

Nature Communications Jul 24;9(1):2895

Siyang Guo, Olga S. Sokolova, Johnson Chung, Shae Padrick, Jeff Gelles, and Bruce L. Goode

 

Species-specific Functions of Twinfilin in Actin Filament Depolymerization

Journal of Molecular Biology Sep 14;430(18 Pt B):3323-3336

Hilton DM, Aguilar RM, Johnston AB, and Goode BL

 

GMF as an Actin Network Remodeling Factor

Trends Cell Biol. May 18. pii: S0962-8924(18)30072-2.

Goode BL, Sweeney MO, Eskin JA

Structural basis of actin monomer re-charging by cyclase-associated protein

Nature Communications May 14;9(1):1892. doi: 10.1038/s41467-018-04231-7

Tommi Kotila, Konstantin Kogan, Giray Enkavi, Siyang Guo, Ilpo Vattulainen, Bruce L. Goode & Pekka Lappalainen

 

Rapid Production of Pure Recombinant Actin Isoforms in Pichia

Journal of Cell Science : jcs.213827 doi: 10.1242/jcs.213827

Tomoyuki Hatano, Salvatore Alioto, Emanuele Roscioli, Saravanan Palani, Scott T Clarke, Anton Kamnev, Juan Ramon Hernandez-Fernaud, Lavanya Sivashanmugam, Bernardo Chapa-Y-Lazo, Alexandra Jones, Robert Robinson, Karuna Sampath, Masanori Mishima, Andrew D McAinsh, Bruce Goode, and Mohan Balasubramaniam

 

A Flow Cytometry-Based Phenotypic Screen To Identify Novel Endocytic Factors in Saccharomyces cerevisiae

G3: Genes, Genomes, Genetics. 2018 Mar 14. pii: g3.200102.2018. doi: 10.1534/g3.118.200102.

Kristie Wrasman, Salvatore Alioto, Yorke Zhang, Kyle Hoban, Marjon Khairy, Bruce Goode, Beverly Wendland

 

     2017               

 

Profilin Directly Promotes Microtubule Growth Through Residues Mutated in Amyotrophic Lateral Sclerosis

Current Biology, 2017  Nov 1. pii: S0960-9822(17)31305-2.

Jessica L. Henty-Ridilla, M. Angeles Juanes, and Bruce L. Goode

APC nucleates actin assembly to drive cell migration and microtubule-induced focal adhesion turnover

Journal of Cell Biology, 2017 Sep 4;216(9):2859-2875.

M. Angeles Juanes, Habib Bouguenina, Julian A. Eskin, Richa Jaiswal, Ali Badache and Bruce L. Goode

 

Structural basis of Arp2/3 complex inhibition by GMF, Coronin, and Arpin

Journal of Molecular Biology, 2017 Jan 20;429(2):237-248.

Sokolova OS, Chemeris A, Guo S, Alioto S, Gandhi M, Padrick S, Pechnikova E, David V, Gautreau A, and Goode BL.

 

     2016      

 

Tropomyosin and profilin cooperate to promote formin-mediated actin nucleation and drive yeast actin cable assembly

Current Biology, 2016 Nov 15. pii: S0960-9822(16)31138-1.
Salvatore L. Alioto, Mikael V. Garabadian, Danielle Bellavance, and Bruce L. Goode ​

 

Accelerated actin filament polymerization from microtubule plus ends

Science. 2016 May 20;352(6288):1004-9.

Henty-Ridilla JL, Rankova A, Eskin JA, Kenny K, Goode BL.

TIRF microscopy analysis of human Cof1, Cof2, and ADF effects on actin filament severing and turnover

J. Mol. Biol. 2016 Mar 17. pii: S0022-2836(16)00192-3.
Chin, S.M., Jansen, S., and Goode, B.L.

Design Principles of Length Control of Cytoskeletal Structures

Ann. Rev. Biophys. 2016 June.
Mohapatra, L., Goode, B.L., Jelenkovic, P., Phillips, R., and Kondev, J.

Common formin-regulating sequences in Smy1 and Bud14 are required for the control of actin cable assembly in vivo

Mol. Biol. Cell. 2016 Mar 1; 27(5):828-37.
Eskin, J.A., Rankova, A., Johnston, A.B., Alioto, S.L., and Goode, B.L.

 

     2015      

 

High Speed Depolymerization at Actin Filament Ends Jointly Catalyzed by Twinfilin and Srv2/CAP

Nat. Cell Biol. 2015 Sep 11; 17(11): 1504-1511.
Johnston, A.J., Collins, A., and Goode, B.L.

Single-molecule visualization of a formin-capping protein 'decision complex' at the actin filament barbed-end

Nat. Comm. 2015 Sep 11; 6: 8707-8024.
Bombardier, J., Eskin, J.A., Jaiswal, R., Correa, I.R., Xu, M-Q, Goode, B.L., and Gelles, J.

Coronin enhances actin filament severing by recruiting cofilin to filament sides and altering F-actin conformation

J. Mol. Biol. 2015 Aug 15; 427(19): 3137-3147.
Mikati, M.A.*, Breitsprecher, D.*, Jansen, S.*, Reisler, E., and Goode, B.L

Combinatorial genetic analysis of a network of actin disassembly-promoting factors

Cytoskeleton. 2015 Jul 3; 72(7): 349-361.
Ydenberg, C.A., Johnston, A., Weinstein, J., Bellavance, D., Jansen, S., and Goode, B.L.

 

Structure of a Bud6/actin complex reveas a novel WH2-like actin monomer recruitment motif

Structure. 2015 May 15; 23: 1-8.
Park, E., Graziano, B.R., Zheng W., Garabedian, M., Goode, B.L., and Eck, M.J.

Antenna Mechanism of Length Control of Actin Cables

PLoS Comput Biol. 2015 Jun 24;11(6):e1004160. doi: 10.1371/journal.pcbi.1004160. eCollection 2015 Jun.

Mohapatra L, Goode BL, Kondev J.

 

Structural basis for mutation-induced destabilization of Profilin 1 in ALS

Proc. Nat. Acad. Sci. 2015 Jun 30; 112(26):7984-9.
Boopathy, S., Silvas, T., Tischbein, M., Jansen, S., Shandilya, S.M.D., Zitzewitz, J.A., Landers, J.E., Goode, B.L., Schiffer, C.A., and Bosco, D.A.

Single molecule imaging of a three-component ordered actin disassembly mechanism

Nat. Comm. 2015 April 17; (6):7202.
Jansen, S., Collins, A., Chin, S.M., Ydenberg, C.A., Gelles, J. and Goode, B.L.

 

     2014      

 

A novel role for WAVE1 in controlling actin network growth rate and architecture

Mol. Biol. Cell. 2014 December 3. E14-10-1477
Sweeney, M.O., Collins, A., Padrick, S.B., and Goode, B.L.

Structure and mechanism of mouse cyclase-associated protein (CAP1) in regulating actin dynamics

J. Biol. Chem. 2014 Oct 31; 289(44):30732-42.
Jansen, S., Collins, A., Golden, L., Sokolova, O., and Goode, B.L.

GMF promotes leading edge dynamics and collective cell migration in vivo

Curr. Biol. 2014 Nov 3; 24(21):2533-40.
Poukkula, M., Hakala, M., Pentinmikko, N., Sweeney, M., Jansen, S., Mattila, J., Hietakangas, V., Goode, B.L., and Lappalainen, P.

 

S. cerevisiae Kelch proteins and Bud14 form a stable 520 kDa formin-regulatory complex that controls actin cable assembly and cell morphogenesis

J. Biol. Chem. 2014 June 27; 289(26):18290-301.
Gould, C.J., Chesarone-Cataldo, M., Alioto, S.L., Salin, B., Sagot, I., and Goode B.L.

 

The F-BAR protein Hof1 tunes formin activity to sculpt actin cables during polarized growth

Mol. Biol. Cell. 2014 June 5; 25(11):1730-43.
Graziano, B.R., Yu, H-Y., Alioto, S.L., Eskin, J.A., Ydenberg, C.A., Waterman, D.P., Garabedian, M., and Goode B.L.

Single-molecule studies of actin assembly and disassembly factors

Meth Enz. 2014 Mar 10; 540:95-117. 
Smith, B., Gelles J., and Goode B.L.

Autonomous and in trans functions for the two halves of Srv2/CAP in promoting actin turnover

Cytoskeleton. 2014 June; 71(6):351-60.
Chaudhry, F., Jansen, S., Little, K., Suarez, C., Boujemaa-Paterski, R., Blanchoin, L., and Goode B.L.

 

Critical roles for multiple formins during cardiac myofibril development and repair

Mol Biol Cell. 2014 Jan 15; doi: 10.1091/mbc.E13-08-0443.
Rosado, M., Barber, C.F., Berciu, C., Feldman, S., Birren, S.J., Nicastro, D., Goode, B.L.

Essential and non-redundant roles for Diaphanous formins in cortical microtubule capture and directed cell migration

Mol Biol Cell. 2014 Mar; 25(5):658-68.
Daou, P., Hasan, S., Breitsprecher, D., Baudelet, E., Camoin, L., Audebert, S., Goode, B.L., Badache, A.

 

     2013      

 

Three-color single-molecule imaging shows WASP release from the nascent branch triggers actin nucleation by Arp2/3 complex

eLife. 2013 Sep 3; 2:e01008. 
Smith, B.A., Padrick, S.B., Doolittle, L.K., Daugherty-Clarke, K., Corrêa Jr., I.R., Xu, M-Q., Goode, B.L., Rosen, M.K., Gelles, J.

 

The Formin Daam1 and Fascin Directly Collaborate to Promote Filopodia Formation

Curr. Biol. 2013 Jul 22; 23(14):1373-9.
Jaiswal, R., Breitsprecher, D., Collins, A.,Corrêa Jr., I.R., Xu, M-Q., and Goode, B.L.

 

GMF severs actin-Arp2/3 complex branch junctions by a cofilin-like mechanism

Curr. Biol. 2013 June 7; 23(12):1037-45.
Ydenberg, C.A., Padrick, S.B., Sweeney, M.O., Gandhi, M., Sokolova, O., and Goode, B.L.

 

Drosophila homologues of Adenomatous Polyposis Coli (APC) and the formin Diaphanous collaborate by a conserved mechanism to stimulate actin filament assembly

J. Biol. Chem. 2013 May 10; 288(19):13897-905.
Jaiswal, R., Stepanik, V., Rankova, A., Molinar, O., Goode, B.L. and McCartney, B.M.

 

Ligand-induced activation of a formin-NPF pair leads to collaborative actin nucleation

J Cell Biol. 2013 May 13; 201(4):595-611.
Graziano, B.R., Jonasson, E.M., Pullen, J.G., Gould, C.J., and Goode, B.L.

 

Formins at a glance

J Cell Sci. 2013 Jan 1; 126(Pt 1):1-7. 
Breitsprecher, D., and Goode, B.L.

Pathway of actin filament branch formation by Arp2/3 complex revealed by single molecule imaging

PNAS. Jan 4, 2013; doi:10.1073/pnas.1211164110
Smith B.A., Daugherty-Clarke, K., Goode, B.L, and Gelles, J.

Srv2/cyclase-associated protein forms hexameric shurikens that directly catalyze actin filament severing by cofilin

Mol Biol Cell. 2013 Jan; 24(1):31-41. doi:10.1091/mbc.E12-08-0589.

Chaudhry F, Breitsprecher D, Little K, Sharov G, Sokolova O and Goode BL.

 

     2012      

 

Structure of the formin-interaction domain of the actin nucleation-promoting factor Bud6

Proc Natl Acad Sci U S A. 2012 Dec 11;109(50):E3424-33. doi: 10.1073/pnas.1203035109.
Tu D, Graziano BR, Park E, Zheng W, Li Y, Goode BL, Eck MJ.

Structure and activity of full-length formin mDia1

Cytoskeleton (Hoboken). 2012 Jun;69(6):393-405. doi: 10.1002/cm.21033.
Maiti S, Michelot A, Gould C, Blanchoin L, Sokolova O, Goode BL.

Rocket launcher mechanism of collaborative actin assembly defined by single-molecule imaging

Science. 2012 Jun 1;336(6085):1164-8. doi: 10.1126/science.1218062.
Breitsprecher D, Jaiswal R, Bombardier JP, Gould CJ, Gelles J, Goode BL.

 

     2011      

 

Cease-fire at the leading edge: new perspectives on actin filament branching, debranching, and cross-linking

Cytoskeleton (Hoboken). 2011 Nov;68(11):596-602. doi: 10.1002/cm.20543.

Ydenberg CA, Smith BA, Breitsprecher D, Gelles J, Goode BL.

Mechanism and cellular function of Bud6 as an actin nucleation-promoting factor

Mol Biol Cell. 2011 Nov;22(21):4016-28. 

Graziano BR, DuPage AG, Michelot A, Breitsprecher D, Moseley JB, Sagot I, Blanchoin L, Goode BL.

 

Cofilin cooperates with fascin to disassemble filopodial actin filaments

J Cell Sci. 2011 Oct 1;124(Pt 19):3305-18. doi: 10.1242/jcs.086934.

Breitsprecher D, Koestler SA, Chizhov I, Nemethova M, Mueller J, Goode BL, Small JV, Rottner K, Faix J.

 

The myosin passenger protein Smy1 controls actin cable structure and dynamics by acting as a formin damper

Dev Cell. 2011 Aug 16;21(2):217-30. doi: 10.1016/j.devcel.2011.07.004.

Chesarone-Cataldo M, Guérin C, Yu JH, Wedlich-Soldner R, Blanchoin L, Goode BL.

 

Crystal structure of a coiled-coil domain from human ROCK I

PLoS One. 2011 Mar 21;6(3):e18080. doi: 10.1371/journal.pone.0018080.

Tu D, Li Y, Song HK, Toms AV, Gould CJ, Ficarro SB, Marto JA, Goode BL, Eck MJ.

 

The formin DAD domain plays dual roles in autoinhibition and actin nucleation

Curr Biol. 2011 Mar 8;21(5):384-90. doi: 10.1016/j.cub.2011.01.047.

Gould CJ, Maiti S, Michelot A, Graziano BR, Blanchoin L, Goode BL.

Coronin 2A mediates actin-dependent de-repression of inflammatory response genes

Nature. 2011 Feb 17;470(7334):414-8. doi: 10.1038/nature09703.

Huang W, Ghisletti S, Saijo K, Gandhi M, Aouadi M, Tesz GJ, Zhang DX, Yao J, Czech MP, Goode BL, Rosenfeld MG, Glass CK.

 

     2010      

 

Functional surfaces on the actin-binding protein coronin revealed by systematic mutagenesis

J Biol Chem. 2010 Nov 5;285(45):34899-908. doi: 10.1074/jbc.M110.171496.

Gandhi M, Jangi M, Goode BL

Adenomatous polyposis coli protein nucleates actin assembly and synergizes with the formin mDia1

J Cell Biol. 2010 Jun 28;189(7):1087-96. doi: 10.1083/jcb.201001016.

Okada K, Bartolini F, Deaconescu AM, Moseley JB, Dogic Z, Grigorieff N, Gundersen GG, Goode BL.

 

GMF is a cofilin homolog that binds Arp2/3 complex to stimulate filament debranching and inhibit actin nucleation

Curr Biol. 2010 May 11;20(9):861-7. doi: 10.1016/j.cub.2010.03.026.

Gandhi M, Smith BA, Bovellan M, Paavilainen V, Daugherty-Clarke K, Gelles J, Lappalainen P, Goode BL.

 

A central role for the WH2 domain of Srv2/CAP in recharging actin monomers to drive actin turnover in vitro and in vivo

Cytoskeleton (Hoboken). 2010 Feb;67(2):120-33. doi: 10.1002/cm.20429.

Chaudhry F, Little K, Talarico L, Quintero-Monzon O, Goode BL.

The p40/ARPC1 subunit of Arp2/3 complex performs multiple essential roles in WASp-regulated actin nucleation

J Biol Chem. 2010 Mar 12;285(11):8481-91. doi: 10.1074/jbc.M109.054957.

Balcer HI, Daugherty-Clarke K, Goode BL.

Unleashing formins to remodel the actin and microtubule cytoskeletons

Nat Rev Mol Cell Biol. 2010 Jan;11(1):62-74. doi: 10.1038/nrm2816.

Chesarone MA, DuPage AG, Goode BL.

 

     2009      

 

The F-BAR protein Syp1 negatively regulates WASp-Arp2/3 complex activity during endocytic patch formation

Curr Biol. 2009 Dec 15;19(23):1979-87. doi: 10.1016/j.cub.2009.10.062.

Boettner DR, D'Agostino JL, Torres OT, Daugherty-Clarke K, Uygur A, Reider A, Wendland B, Lemmon SK, Goode BL.

 

Coronin switches roles in actin disassembly depending on the nucleotide state of actin

Mol Cell. 2009 May 15;34(3):364-74. doi: 10.1016/j.molcel.2009.02.029.

Gandhi M, Achard V, Blanchoin L, Goode BL.

Displacement of formins from growing barbed ends by bud14 is critical for actin cable architecture and function

Dev Cell. 2009 Feb;16(2):292-302. doi: 10.1016/j.devcel.2008.12.001.

Chesarone M, Gould CJ, Moseley JB, Goode BL.

Reconstitution and dissection of the 600-kDa Srv2/CAP complex: roles for oligomerization and cofilin-actin binding in driving actin turnover

J Biol Chem. 2009 Apr 17;284(16):10923-34. doi: 10.1074/jbc.M808760200.

Quintero-Monzon O, Jonasson EM, Bertling E, Talarico L, Chaudhry F, Sihvo M, Lappalainen P, Goode BL.

 

Actin nucleation and elongation factors: mechanisms and interplay

Curr Opin Cell Biol. 2009 Feb;21(1):28-37. doi: 10.1016/j.ceb.2008.12.001.

Chesarone MA, Goode BL.

​Actin filament labels for localizing protein components in large complexes viewed by electron microscopy

RNA. 2009 Feb;15(2):244-8. doi: 10.1261/rna.1313609.

Stroupe ME, Xu C, Goode BL, Grigorieff N.

 

     2008      

 

Coronin: the double-edged sword of actin dynamics

Subcell Biochem. 2008;48:72-87. doi: 10.1007/978-0-387-09595-0_7.

Gandhi M, Goode BL.

WASp identity theft by a bacterial effector

Dev Cell. 2008 Sep;15(3):333-4. doi: 10.1016/j.devcel.2008.08.010.

Daugherty-Clarke K, Goode BL.

The formin mDia2 stabilizes microtubules independently of its actin nucleation activity

J Cell Biol. 2008 May 5;181(3):523-36. doi: 10.1083/jcb.200709029.

Bartolini F, Moseley JB, Schmoranzer J, Cassimeris L, Goode BL, Gundersen GG.

 

Functional surfaces on the p35/ARPC2 subunit of Arp2/3 complex required for cell growth, actin nucleation, and endocytosis

J Biol Chem. 2008 Jun 13;283(24):16950-9. doi: 10.1074/jbc.M800783200.

Daugherty KM, Goode BL.

Regulation and targeting of the fission yeast formin cdc12p in cytokinesis

Mol Biol Cell. 2008 May;19(5):2208-19. doi: 10.1091/mbc.E07-07-0731.

Yonetani A, Lustig RJ, Moseley JB, Takeda T, Goode BL, Chang F.

 

     2007      

 

Structure of the FH2 domain of Daam1: implications for formin regulation of actin assembly

J Mol Biol. 2007 Jun 22;369(5):1258-69.

Lu J, Meng W, Poy F, Maiti S, Goode BL, Eck MJ.

Mechanism and biological role of profilin-Srv2/CAP interaction

J Cell Sci. 2007 Apr 1;120(Pt 7):1225-34.

Bertling E, Quintero-Monzon O, Mattila PK, Goode BL, Lappalainen P.

 

Mechanism and function of formins in the control of actin assembly

Annu Rev Biochem. 2007;76:593-627.

Goode BL, Eck MJ.

Regulated binding of adenomatous polyposis coli protein to actin

J Biol Chem. 2007 Apr 27;282(17):12661-8. Epub 2007 Feb 8.

Moseley JB, Bartolini F, Okada K, Wen Y, Gundersen GG, Goode BL

 

     2006      

 

The yeast actin cytoskeleton: from cellular function to biochemical mechanism

Microbiol Mol Biol Rev. 2006 Sep;70(3):605-45.

Moseley JB, Goode BL.

Four novel suppressors of gic1 gic2 and their roles in cytokinesis and polarized cell growth in Saccharomyces cerevisiae

Genetics. 2006 Oct;174(2):665-78. Epub 2006 Jul 2.

Gandhi M, Goode BL, Chan CS.

Aip1 and cofilin promote rapid turnover of yeast actin patches and cables: a coordinated mechanism for severing and capping filaments

Mol Biol Cell. 2006 Jul;17(7):2855-68.

Okada K, Ravi H, Smith EM, Goode BL.

Twinfilin is an actin-filament-severing protein and promotes rapid turnover of actin structures in vivo

J Cell Sci. 2006 Apr 15;119(Pt 8):1547-57.

Moseley JB, Okada K, Balcer HI, Kovar DR, Pollard TD, Goode BL.

Formin proteins: purification and measurement of effects on actin assembly

Methods Enzymol. 2006;406:215-34.

Moseley JB, Maiti S, Goode BL.

 

     2005      

 

Dissection of Arp2/3 complex actin nucleation mechanism and distinct roles for its nucleation-promoting factors in Saccharomyces cerevisiae

Genetics. 2005 Sep;171(1):35-47.

D'Agostino JL, Goode BL.

Differential activities and regulation of Saccharomyces cerevisiae formin proteins Bni1 and Bnr1 by Bud6

J Biol Chem. 2005 Jul 29;280(30):28023-33.

Moseley JB, Goode BL.

Structural and functional dissection of the Abp1 ADFH actin-binding domain reveals versatile in vivo adapter functions

Mol Biol Cell. 2005 Jul;16(7):3128-39.

Quintero-Monzon O, Rodal AA, Strokopytov B, Almo SC, Goode BL.

Conformational changes in the Arp2/3 complex leading to actin nucleation

Nat Struct Mol Biol. 2005 Jan;12(1):26-31.

Rodal AA, Sokolova O, Robins DB, Daugherty KM, Hippenmeyer S, Riezman H, Grigorieff N, Goode BL.

Actin and septin ultrastructures at the budding yeast cell cortex

Mol Biol Cell. 2005 Jan;16(1):372-84.

Rodal AA, Kozubowski L, Goode BL, Drubin DG, Hartwig JH.

 

     2004      

 

A high-affinity interaction with ADP-actin monomers underlies the mechanism and in vivo function of Srv2/cyclase-associated protein

Mol Biol Cell. 2004 Nov;15(11):5158-71.

Mattila PK, Quintero-Monzon O, Kugler J, Moseley JB, Almo SC, Lappalainen P, Goode BL.

Crystal structures of a Formin Homology-2 domain reveal a tethered dimer architecture

Cell. 2004 Mar 5;116(5):711-23.

Xu Y, Moseley JB, Sagot I, Poy F, Pellman D, Goode BL, Eck MJ.

A conserved mechanism for Bni1- and mDia1-induced actin assembly and dual regulation of Bni1 by Bud6 and profilin

Mol Biol Cell. 2004 Feb;15(2):896-907.

Moseley JB, Sagot I, Manning AL, Xu Y, Eck MJ, Pellman D, Goode BL.

 

     2003      

 

Coordinated regulation of actin filament turnover by a high-molecular-weight Srv2/CAP complex, cofilin, profilin, and Aip1.

Curr Biol. 2003 Dec 16;13(24):2159-69.

Balcer HI, Goodman AL, Rodal AA, Smith E, Kugler J, Heuser JE, Goode BL.

The Saccharomyces cerevisiae calponin/transgelin homolog Scp1 functions with fimbrin to regulate stability and organization of the actin cytoskeleton

Mol Biol Cell. 2003 Jul;14(7):2617-29.

Goodman A, Goode BL, Matsudaira P, Fink GR.

Negative regulation of yeast WASp by two SH3 domain-containing proteins

Curr Biol. 2003 Jun 17;13(12):1000-8.

Rodal AA, Manning AL, Goode BL, Drubin DG.

 

     2001      

 

Modular complexes that regulate actin assembly in budding yeast

Curr Opin Microbiol. 2001 Dec;4(6):703-12.

Goode BL, Rodal AA.

Yeast Eps15-like endocytic protein, Pan1p, activates the Arp2/3 complex

Nat Cell Biol. 2001 Jul;3(7):687-90.

Duncan MC, Cope MJ, Goode BL, Wendland B, Drubin DG.

Activation of the Arp2/3 complex by the actin filament binding protein Abp1p

J Cell Biol. 2001 Apr 30;153(3):627-34.

Goode BL, Rodal AA, Barnes G, Drubin DG.

 

     2000      

 

Structural and functional differences between 3-repeat and 4-repeat tau isoforms. Implications for normal tau function and the onset of neurodegenetative disease

J Biol Chem. 2000 Dec 8;275(49):38182-9.

Goode BL, Chau M, Denis PE, Feinstein SC.

Functional cooperation between the microtubule and actin cytoskeletons

Curr Opin Cell Biol. 2000 Feb;12(1):63-71.

Goode BL, Drubin DG, Barnes G.

 

     1999      

 

Coronin promotes the rapid assembly and cross-linking of actin filaments and may link the actin and microtubule cytoskeletons in yeast

J Cell Biol. 1999 Jan 11;144(1):83-98.

Goode BL1, Wong JJ, Butty AC, Peter M, McCormack AL, Yates JR, Drubin DG, Barnes G.

 

     1998     

 

Saccharomyces cerevisiae Duo1p and Dam1p, novel proteins involved in mitotic spindle function

J Cell Biol. 1998 Nov 16;143(4):1029-40.

Hofmann C, Cheeseman IM, Goode BL, McDonald KL, Barnes G, Drubin DG.

Regulation of the cortical actin cytoskeleton in budding yeast by twinfilin, a ubiquitous actin monomer-sequestering protein

J Cell Biol. 1998 Aug 10;142(3):723-33.

Goode BL, Drubin DG, Lappalainen P.

 

     1997     

 

Functional interactions between the proline-rich and repeat regions of tau enhance microtubule binding and assembly

Mol Biol Cell. 1997 Feb;8(2):353-65.

Goode BL, Denis PE, Panda D, Radeke MJ, Miller HP, Wilson L, Feinstein SC.

 

     1995     

 

Kinetic stabilization of microtubule dynamics at steady state by tau and microtubule-binding domains of tau

Biochemistry. 1995 Sep 5;34(35):11117-27.

Panda D, Goode BL, Feinstein SC, Wilson L.

 

     1994     

 

Identification of a novel microtubule binding and assembly domain in the developmentally regulated inter-repeat region of tau

J Cell Biol. 1994 Mar;124(5):769-82.

Goode BL, Feinstein SC.

 

     1993     

 

Molecular analysis of the nerve growth factor inducible ornithine decarboxylase gene in PC12 cells

J Neurosci Res. 1993 Feb 15;34(3):304-14.

Muller SR, Huff SY, Goode BL, Marschall L, Chang J, Feinstein SC.

 

     1992     

"Speedprep" purification of template for double-stranded DNA sequencing

Biotechniques. 1992 Mar;12(3):374-5.

Goode BL, Feinstein SC.

 

     1990     

 

Restriction mapping of recombinant lambda DNA molecules using pulsed field gel electrophoresis

Anal Biochem. 1990 Nov 15;191(1):70-4.

Goode BL, Feinstein SC.

     2024     

 

Improved tools for live imaging of F-actin structures in yeast.

Mol Biol Cell. 2024 Jul 18; mbcE24050212T. doi: 10.1091/mbc.E24-05-0212-T. Online ahead of print.

Alison CE Wirshing, Bruce L Goode

The role of yeast formins and their regulators Bud6 and Bil2 in the pheromone response. 

Mol Biol Cell. 2024 Apr 24; mbcE23110459. doi: 10.1091/mbc.E23-11-0459 103(1):151378.

Joseph O MagliozziThomas J RandsSudati ShresthaWilliam C SimkeNiklas E HaseM Angeles JuanesJoshua B KelleyBruce L Goode

Direct observation of cortactin protecting Arp2/3-actin filament branch junctions from GMF-mediated destabilization 

Eur J Cell Biol. 2024 Mar; 103(1):151378. doi: 10.1016/j.ejcb.2023.151378. Epub 2023 Dec 5.

Emma R. McGuirk, Neha Koundinya, Priyashree Nagarajan, Shae B. Padrick, Bruce L. Goode

     2023     

Universal length fluctuations of actin structures in cells.

eLife (in press). 2023 Dec 4;12:RP91574. doi: 10.7554/eLife.91574.1.

Aldric Rosario, Shane G. McInally, Predrag R. Jelenkovic, Bruce L. Goode and Jane Kondev

 

Mechanisms of Actin Disassembly and Turnover

J Cell Biol​. 2023 Dec 4;222(12):e202309021. doi: 10.1083/jcb.202309021. Epub 2023 Nov 10.

Bruce L. Goode, Julian Eskin and Shashank Shekhar

 

Length control emerges from cytoskeletal network geometry

bioRxiv [Preprint]. 2023 Nov 29: 2023.11.28.569063. doi: 10.1101/2023.11.28.569063.

Shane G. McInally, Alexander JB. Reading, Aldric Rosario, Predrag R. Jelenkovic, Bruce L. Goode, and Jane Kondev

Cyclase-associated protein (CAP) interacts with actin filament barbed ends to promote depolymerization and formin displacement

J Biol Chem​. 2023 Oct 18:105367. doi: 10.1016/j.jbc.2023.105367. Online ahead of print.

Nikita Alimov, Gregory J Hoeprich, Shae B Padrick, and Bruce L Goode

Cytosolic concentrations of actin binding proteins and the implications for in vivo F-actin turnover

J Cell Biol​. 2023 Dec 4;222(12):e202306036. doi: 10.1083/jcb.202306036. Epub 2023 Oct 6.

Sofia Gonzalez Rodriguez, Alison C E Wirshing, Anya L Goodman, and Bruce L Goode

Dynamic remodeling of actin networks by cyclase-associated protein and CAP-Abp1 complexes

Curr Biol​. 2023 Sep 28:S0960-9822(23)01278-2. doi: 10.1016/j.cub.2023.09.032. Online ahead of print.

Siyang Guo, Gregory J Hoeprich, Joseph O Magliozzi, Jeff Gelles, and Bruce L Goode 

Bitesize bundles F-actin and influences actin remodeling in syncytial Drosophila embryo development

bioRxiv​. 2023 Apr 17:2023.04.17.537198. doi: 10.1101/2023.04.17.537198. Preprint.

Anna R Yeh, Gregory J Hoeprich, Bruce L Goode, and Adam C Martin

Evolutionary tuning of barbed end competition allows simultaneous construction of architecturally distinct actin structures

J Cell Biol​. 2023 Apr 3;222(4):e202209105. doi: 10.1083/jcb.202209105. Epub 2023 Feb 2.

Alison C.E. Wirshing, Sofia Gonzalez Rodriguez, and Bruce L. Goode 

Tyrosyl-tRNA synthetase has a noncanonical function in actin bundling

Nat Commun​. 2023 Mar 8;14(1):999. doi: 10.1038/s41467-023-35908-3.

Biljana Ermanoska, Bob Asselbergh, Laura Morant, Maria-Luise Petrovic-Erfurth, Seyyedmohsen Hosseinibarkooie, Ricardo Leitão-Gonçalves, Leonardo Almeida-Souza, Sven Bervoets, Litao Sun, LaTasha Lee, Derek Atkinson, Akram Khanghahi, Ivaylo Tournev, Patrick Callaerts, Patrik Verstreken, Xiang-Lei Yang, Brunhilde Wirth, Avital A Rodal, Vincent Timmerman, Bruce L Goode, Tanja A Godenschwege, and Albena Jordanova

     2022     

Single-molecule analysis of actin filament debranching by cofilin and GMF

Proc Natl Acad Sci USA. 2022 Jul 19;119(29):e2115129119. doi: 10.1073/pnas.2115129119. Epub 2022 Jul 11.

Johnson ChungBruce L. Goode, and Jeff Gelles

Quantitative Analysis of Actin Cable Length in Yeast

Bio Protoc. 2022 May 5;12(9):e4402. doi: 10.21769/BioProtoc.4402. eCollection 2022 May 5.

Shane G. McInally, Jane Kondev, and Bruce L. Goode

Extensile to contractile transition in active microtubule-actin composites generates layered asters with programmable lifetimes

Proc Natl Acad Sci USA. 2022 Feb 1;119(5):e2115895119. doi: 10.1073/pnas.2115895119

John BerezneyBruce L. GoodeSeth Fraden, and Zvonimir Dogic

Single-molecule imaging of IQGAP1 regulating actin filament dynamics

Mol Biol Cell. 2022 Jan 1;33(1):ar2. doi: 10.1091/mbc.E21-04-0211. Epub 2021 Nov 3.

Gregory J. Hoeprich, Amy N. Sinclair, Shashank Shekhar, and Bruce L. Goode

     2021     

 

Scaling of subcellular actin structures with cell length through decelerated growth

eLife. 2021 Jun 11;10:e68424. doi:10.7 554 /eLife.684 24

Shane G. McInally, Jane Kondev, and Bruce L. Goode

Bil2 is a novel inhibitor of the yeast formin Bnr1 required for proper actin cable organization and polarized secretion

Front. Cell Dev. Biol. 2021 Feb 9;9:634587. doi: 10.3389/fcell.2021.634587.

Thomas J. Rands and Bruce L. Goode

DAAM2 Variants Cause Nephrotic Syndrome via Actin Dysregulation

Am J Hum Genet. 2020 Dec 3;107(6):1113-1128. doi: 10.1016/j.ajhg.2020.11.008.

Ronen Schneider, Konstantin Deutsch, Gregory J Hoeprich, Jonathan Marquez, Tobias Hermle, Daniela A Braun, Steve Seltzsam, Thomas M Kitzler, Youying Mao, Florian Buerger, Amar J Majmundar, Ana C Onuchic-Whitford, Caroline M Kolvenbach, Luca Schierbaum, Sophia Schneider, Abdul A Halawi, Makiko Nakayama, Nina Mann, Dervla M Connaughton, Verena Klämbt, Matias Wagner, Korbinian M Riedhammer, Lutz Renders, Yoshichika Katsura, Dean Thumkeo, Neveen A Soliman, Shrikant Mane, Richard P Lifton, Shirlee Shril, Mustafa K Khokha, Julia Hoefele, Bruce L Goode, Friedhelm Hildebrandt

Twinfilin bypasses assembly conditions and actin filament aging to drive barbed end depolymerization

J Cell Biol. 2021 Jan 4;220(1):e202006022. doi: 10.1083/jcb.202006022. 

Shashank Shekhar, Gregory J. Hoeprich, Jeff Gelles, and Bruce L. Goode

     2020     

EB1 Directly Regulates APC-Mediated Actin Nucleation

Current Biology. 2020 Sep 28:S0960-9822(20)31284-7. doi: 10.1016/j.cub.2020.08.094.

Maria Angeles Juanes, Colby Fees, Gregory J. Hoeprich, Richa Jaiswal, and Bruce L. Goode

Cell-substrate adhesion drives Scar/WAVE activation and phosphorylation by a Ste20-family kinase, which controls pseudopod lifetime

PLoS Biol. 2020 Aug 3;18(8):e3000774. doi: 10.1371/journal.pbio.3000774.

Singh SP, Thomason PA, Lilla S, Schaks M, Tang Q, Goode BL, Machesky LM, Rottner K, Insall RH.

Cofilin loss in Drosophila muscles contributes to muscle weakness through defective sarcomerogenesis during muscle growth

Cell Reports. Vol 32, Issue 3, 21 July 2020

Mridula Balakrishnan, Shannon F. Yu, Samantha M. Chin, David B. Soffar, Stefanie 
E. Windner, Bruce L. Goode, and Mary K. Baylies.

 

WAVE 1 and WAVE 2 have distinct and overlapping roles in controlling actin assembly at the leading edge

MBoC. 2020 Sep 15;31(20):2168-2178. doi: 10.1091/mbc.E19-12-0705. Epub 2020 Jul 22.

Qing Tang, Matthias Schaks, Neha Koundinya, Changsong Yang, Luther W. Pollard, Tatyana M. Svitkina, Klemens Rottner, Bruce L. Goode.

bottom of page