https://goodelab.org/home daily 1.0 2025-04-03 https://images.squarespace-cdn.com/content/v1/6717ecee43306f623d8c9720/b28b0486-36cb-4f06-ba09-64771bf0f453/K+-+remodeling+1+color+resized+rotated.gif https://images.squarespace-cdn.com/content/v1/6717ecee43306f623d8c9720/665ac087-ff7d-4ad9-a90f-c55c97fd21cd/IMG_1973.jpg https://images.squarespace-cdn.com/content/v1/6717ecee43306f623d8c9720/1729624234594-6J9CHL7O1YDI1IQC58P8/unsplash-image-_Zua2hyvTBk.jpg https://goodelab.org/research-overview daily 0.75 2024-10-28 https://images.squarespace-cdn.com/content/v1/6717ecee43306f623d8c9720/cf4a3d9e-ff45-4f0a-8dd8-6383563a51f7/G+-+CLIP%2BActin+in+N2A+%28Jess%29+resize.gif Research Overview N2A cell expressing mCherry-CLIP-170 (magenta) and GFP-actin (yellow). https://images.squarespace-cdn.com/content/v1/6717ecee43306f623d8c9720/6f1a7127-683c-4eaa-9470-3c71b929e56b/K+-+remodeling+1+color+resized+rotated.gif Research Overview Novel actin network remodeling activity by a combination of actin-binding proteins. https://images.squarespace-cdn.com/content/v1/6717ecee43306f623d8c9720/202a4e3e-4078-42ed-8b3c-66f87174bb6f/B+-+Rocket-Launcher-smaller.gif Research Overview Collaborative "rocket launcher" mechanism of actin assembly by APC (blue) and formin (red). Left: TIRFM movie. Right: animation. https://images.squarespace-cdn.com/content/v1/6717ecee43306f623d8c9720/c95eaf79-ec8c-4878-b863-545e0b4c38ad/B16+cell+%28slow%29.gif Research Overview Branched actin network assembly at leading edge in WT B16 melanoma cell. https://images.squarespace-cdn.com/content/v1/6717ecee43306f623d8c9720/587bec92-0e3a-4cd2-891a-f5a60f6f0d50/I+-+depolymerization+%2B+severing-resize.gif Research Overview Severing of filaments by cofilin (red arrows) and rapid end-depolymerization by Twinfilin and Srv2/CAP (yellow+blue arrows). https://images.squarespace-cdn.com/content/v1/6717ecee43306f623d8c9720/66c3b6fc-e9e8-4bfb-9ca0-51454e7f61d2/Abp140-GFP.gif Research Overview Dynamic actin cables labeled with Abp140-GFP in a budding yeast imaged on a spinning disk confocal microscope. https://images.squarespace-cdn.com/content/v1/6717ecee43306f623d8c9720/54ab261c-eb00-42d5-817b-81c6fb9ee963/A+-+Jess+taser+%28MT+CLIP+actin%29-resize.gif Research Overview Ultrafast assembly of actin (blue) from the growing plus end microtubule (magenta), mediated by CLIP-170, EB1, and Formin (yellow). https://images.squarespace-cdn.com/content/v1/6717ecee43306f623d8c9720/5ccc1ca4-ed1e-412f-a1c1-f63b7342f580/L+-+remodeling+%282+color%29+resize.gif Research Overview Remodeling of a branched actin network comprised of red and green filaments. https://images.squarespace-cdn.com/content/v1/6717ecee43306f623d8c9720/7ec1ca71-b8c1-4615-82c5-f9faf6ed3176/Formin-regulators-for-website-2.png Research Overview Illustration of different formin-interacting proteins and their regulatory effects https://images.squarespace-cdn.com/content/v1/6717ecee43306f623d8c9720/520442cf-dff7-4e0b-b749-1de55ce62ef3/F---Rat-cortical-neurons-transfected-with-GFP-resized.jpg Research Overview Rat cortical neuron expressing GFP. https://images.squarespace-cdn.com/content/v1/6717ecee43306f623d8c9720/8821aaed-ea09-4c21-8787-cefe84fd82a5/M+-+debranching+resized.gif Research Overview GMF-induced debranching of Arp2/3-generated 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